Life-threatening Blood-Brain Barrier Disruption after Coiling of Unruptured Intracranial Aneurysm: Role of Immediate Postembolization CT scanning

generally used for diagnostic and interventional cerebral angiography. Several cases with minor complications resulting from nonionic CM have been reported (1-4). Regarding adverse events of CM, abnormal contrast enhancement have frequently been encountered up to 43% in clinical practices, and appearance of these patterns on CT scans can be various such as cortical, subarachnoid, intraventricular, and striatal enhancement (5, 6). Temporary disruption of bloodbrain barrier (BBB) permeability has been the primary explanation for such abnormal CT findings (4, 5, 7). However, in most previous reports, abnormal enhancement after angiography had reported no symptoms, or mild transient symptoms. We have practiced immediate postembolization CT scans on every subject who underwent neurointerventional treatment for the purpose of earlier detection of the aforementioned complications (5). Recently, we experienced a patient with BBB disruption who revealed typical radiological findings and simultaneously showed serious neurological deterioration.